A couple who live on different sides of the divide of life and death discover just how many boundaries love can cross in this romantic comic fantasy. Elizabeth (Reese Witherspoon) is a hardworking and dedicated medical resident who, after 20 hours on duty, is heading home when she falls asleep at the wheel of her car and is involved in a fatal auto accident. Several weeks later, a man named David (Mark Ruffalo) takes over the lease on Elizabeth's apartment, but he discovers that she hasn't quite vacated the building.